Manuel Serrano is a researcher at the Spanish National Cancer Research Centre (CNIO), in Madrid, and Director of the Molecular Oncology Program of the CNIO. After completing his studies and PhD in Madrid, M.S. joined the laboratory of David Beach, at Cold Spring Harbor Laboratory, NY, USA, as postdoctoral fellow from 1992 to 1996. During this time, M.S. made two of his most important contributions, namely, the discovery of the tumor suppressor p16, and the characterization of the cell response known as oncogene-induced senescence, the latter in collaboration with Scott Lowe. In 1997, M.S. established his research group in Madrid. The main contributions of the Serrano´s laboratory are related to the concept of senescence and the anti-aging activity of tumor suppressors. More recently, Serrano´s group has worked on the connection between tumor suppressors and metabolism, and it has demonstrated the feasibility of embryonic reprogramming within live adult organisms (this last discovery was considered "Advance of the Year 2013 by Nature Medicine").
Bibliometric data from the ISI (December 2015):
Total number of publications: 223
Total number of citations: 23,093
Average number of citations per paper: 104 highly cited papers (>300 citations): 16
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